Origin of Oxycodone:
Oxycodone is a semi-synthetic sedative that was first made in 1916 from thebaine, a compound found in poppy plants known as thebaine. It gives resemblance to with other opiate drugs like for example morphine and heroin and often used as their replacement.
Oxycodone was first created to experiment non-addictive options to these narcotics medications which were normally utilized as a part of prescription earlier during World War I.
Oxycodone is an opioid that is derived from OxyContin which was formulated in Germany in 1916. This drug was formulated with an intention of being served as a superior pharmaceutical product that various different opioids, for example, heroin, codeine, and even morphine. Previously, before this drug was formulated many individuals were known to be dependent on heroin and its substitutes and were prone to show symptoms of drug abuse.
Heroin was extremely addictive since its discovery. After heroin’s boycott in America, two German researchers made oxycodone. It was claimed as a non-addictive, semi-synthetic substitute for heroin, morphine, and opium.
Oxycodone was first discovered in the U.S. in 1939, yet it wasn’t until Purdue Pharma started producing OxyContin in the United States in 1996 from where it’s utilization started. OxyContin has had its good and bad times in the market of professionally prescribed medications, and by 2001 it was one of the top-rated opiate used as an instant relieving drug across the country.
Uses of Oxycodone:
Oxycodone is a sedative painkiller that works by changing the way the mind reacts to pain. It is prescribed to treat pain in all forms ranging in degree from moderate to severe. It is considered as a powerful pain-relieving tablet for many types of pain and is particularly valuable for paroxysmal spontaneous pain, chronic and steady pain, allodynia related with post-herpetic neuralgia, and is likewise increasingly utilized as an effective drug in the management of cancer-related pain and agony.
Oxycodone has been found to enhance the personal satisfaction of patients when in pain. Nowadays it is considered as an alternative to morphine and hydromorphone. Studies also suggest that its superior to morphine in the treatment of various chronic pain diseases as it has an immediate onset and a prolonged half-life.
Oxycodone is a potent analgesic and is found mainly in two forms – extended-releasing tablets and immediate-releasing tablets. It also comes in a form of a solution and capsules.
Along with that, it is also supplied in different strengths ranging from 5mg, 10mg, 15mg, 20mg, 30mg, 40mg and 80mg. Depending on the type and severity of pain these drugs are prescribed. Initially, low dosages are preferred.
It is regularly provided under the brand names Oxycontin, Percocet, Roxicodone, and Percodan. It is also manufactured in combination with other drugs that contain ibuprofen, acetaminophen, and aspirin along with Oxycodone to increase its efficacy.
Side Effects and Drug Abuse:
Common side effects:
Some of the common side effects of Oxycodone are as follows
a. Respiratory Impairment
b. Headaches and Dizziness
c. Increase pressure of spinal and cerebral fluid
d. Nausea and Vomiting
e. Low Blood Pressure
f. Dry Mouth
h. Flushing and Sweating
j. Mood Changes
k. Stomach Pain and Loss of Appetite
l. Hoarseness of voice, and
m. Itching, Allergies, and Hives
Some side effects are also serious and life-threatening. They are as follows:
a. Extreme excitability
b. Irregular chest pain
c. Swelling of face, mouth, tongue and extremities
d. Extreme drowsiness
e. Postural Hypotension
f. Excessive sleepiness
g. Limp or Weak muscles
h. Narrowing or widening of pupils
i. Cold calmly skin
j. Breathing irregularities leading to shortness of breath
k. Heart Failure, and
When one is prescribed with Oxycodone, one should always keep them encased in a closed tight container and out of reach of children. This drug needs to be stored at room temperature, away from light and not in contact with heat and moisture. Throw away the medications once their use is over or flush them out in the drain so others don’t take it and are affected by it. As advisable likewise for other medications also, keep them out of sight and reach of children.